Primary Monoclonal

Antigen: full length recombinant human HMGB1 Host: mouse, clone IMG19N10B7 Isotype: IgG2b? Cross Reactivity: (+) human and mouse HMGB1 Applications: FC, IHC (paraffin-embedded tissue), and WB HMGB1 is a necessary and sufficient mediator of inflammation during sterile and infection-associated...

Antigen: human adropin amino acids 34-76 Host: mouse, clone CC1133F5 Isotype: IgG1 Cross Reactivity: (+) human adropin Application(s): ELISA and WB

Antigen: human PAF receptor amino acids 260-269 Host: mouse, 11A4 clone 21 Cross Reactivity: (+) human, bovine, and porcine PAF receptor Application(s): FC, ICC; does not work for WB PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear...

Immunogen: Full length recombinant PAD4 protein Clone: 11F9 Host: Mouse Isotype: IgG1 Species Reactivity: (+) Human PAD4 Applications: ELISA, WB

Antigen: human Akt1 containing phospho-serine473 Host: mouse, clone 104A282 Isotype: IgG2κ Cross Reactivity: (+) human and mouse Akt1 Application(s): IP and WB Akt/PKB is a serine/threonine kinase that mediates cell survival and is thought to be a critical factor in the genesis of cancer. The...

Antigen: synthetic peptide from human histone H3 Host: mouse, clone 117C826 Cross-Reactivity: (+) Human Histone H3 Application(s): WB H3 phosphorylation at serine 28 is coupled with mitotic chromosome condensation in diverse mammalian cell lines.

Antigen: fusion protein corresponding to amino acids 77-186 of human TRAF5 Host: mouse Cross Reactivity: (+) human and mouse TRAF5 Application(s): WB TRAF5, an adaptor protein that mediates signal transduction from TNF receptors, is implicated in NF-kB and c-Jun NH(2)-terminal...

Antigen: human caspase-8 amino acids PVETDSEEQP Host: mouse, clone 90A992 Isotype: IgG1 Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8 Application(s): FC, IHC (paraffin-embedded tissue), and WB Caspase-8 forms a direct link between the activation of CD95 and the caspase...

Antigen: peptide from human TLR8 within the region of amino acids 750-850 Host: mouse, clone 44C143 Cross Reactivity: (+) human and mouse TLR8 Application(s): FC (intracellular and cell surface), IHC (paraffin-embedded sections), and WB TLRs mediate innate immunity that is essential for microbial...

Antigen: recombinant human IL-33 Host: mouse, clone IL33026B Cross Reactivity: (+) human and mouse IL-33 Application(s): ELISA, IP, and WB IL-33, a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell...

Antigen: hamster brain SAF Host: mouse Isotype: IgG2b Cross Reactivity (PrPc): (+) hamster, mouse, bovine, ovine, and human PrP Application(s): WB

Epitope: Binds to N-terminal amino acids 16-25 of wild-type and mutant p53 Host: Mouse, clone BP53-12 Isotype: IgG2a Species Reactivity: (+) Human p53 Application(s): FC, ICC, IHC (paraffin-embedded sections), and WB Cellular p53, often called the 'guardian of the genome,' is a transcription...

Antigen: oligomeric form of Aβ42 Host: mouse Isotype: IgG2b Cross Reactivity: (+) human Aβ; unaggregated, oligomeric and fibrillar forms of synthetic Aβ42, and unaggregated Aβ40; (−) human APP Application(s): WB, ELISA, ICC, and IP

Antigen: recombinant adenovirus expressing full-length mouse CD36 Host: CD36 null mouse, clone JC63.1 Cross Reactivity: (+) human, mouse, and rat CD36 Application(s): FC, functional blocking, and ICC Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is necessary...

Antigen: human COX-2 amino acids 580-599 Host: mouse, clone CX229 Cross-Reactivity: (+) human and ovine COX-2; (−) mouse, rat, and rabbit COX-2 and COX-1 (all species) Application(s): (+) FC and ICC; (−) IHC and WB Isotype: IgG1 This product is derived by labeling the COX-2 monoclonal...

Immunogen: Full length recombinant PAD2 protein Clone: 9F7 Host: Mouse Isotype: IgG1 Species Reactivity: (+) Human PAD2 Application(s): ELISA, WB

Host: mouse, clone 5F6 Isotype: IgG2b Cross Reactivity: (+) human and mouse MPO Application(s): IF

Antigen: recombinant human ANGPTL3 Host: mouse, clone Kairos-37 Cross Reactivity: (+) human ANGPTL3; (−) human ANGPTL isoforms 1, 2, 4, 6, and 7 Application(s): ELISA and WB ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.

Antigen: human recombinant sPLA2 (type IIA) Host: mouse Cross-Reactivity: (+) human sPLA2 (type IIA); (−) bee venom sPLA2 (type III) and human sPLA2 (type V) Application(s): WB, IHC and IP; other applications not tested Isotype: IgG1 Clone designation: SCACC353

Antigen: recombinant mouse ANGPTL3 Host: rat, clone Kairos3-1541 Cross Reactivity: (+) mouse ANGPTL3; (−) mouse ANGPTL4 and human ANGPTL3 Application(s): ELISA and WB ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.

Immunogen: Recombinant human vimentin protein Host: Mouse Species Reactivity: (+) Human vimentin Cross Reactivity: (+) Citrullinated vimentin Applications: ELISA and WB

Antigen: synthetic peptide corresponding to mouse caspase-14 amino acids 2-18 Host: mouse Cross Reactivity: (+) human and mouse caspase-14 Application(s): FC (intracellular) and WB Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been...

Antigen: recombinant mouse FTO Host: rat, clone FT 342-1 Isotype: IgG2ak Cross Reactivity: (+) mouse and rat FTO; (−) human FTO Application(s): ELISA and WB FTO is associated with type 2 diabetes and positively correlated with other symptoms of the metabolic syndrome, including higher fasting...

Antigen: human TLR9 amino acids 268-284  Host: mouse, clone 26C593.2 Cross Reactivity: (+) canine, equine, human, mouse, rat, and Rhesus monkey TLR9 Application(s): FC (intracellular and cell surface), ICC, IHC (frozen and paraffin), and WB Gene knockout experiments suggest that TLR9 acts as a...