Antigen: human PAF receptor amino acids 260-269
Host: mouse, 11A4 clone 21
Cross Reactivity: (+) human, bovine, and porcine PAF receptor
Application(s): FC, ICC; does not work for WB
PAF is a biologically active phospholipid whose biological effects include activation of platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF increases vascular permeability, decreases cardiac output, induces hypotension, and stimulates uterine contraction.