Antigen: Ba/F3 cell line expressing human TLR4 cell surface antigen
Isotype: IgG2aK
Host: mouse, clone HTA125
Cross Reactivity: (+) human and canine TLR4
Application(s): FC (cell surface and intracellular), ICC, IP, and neutralization
TLR4 is mediator of innate immunity that is essential for microbial recognition and serves as one of the main mediators of LPS signaling.