Persephin is a neurotrophic factor of the glial cell line-derived neurotrophic factor (GDNF) family. Persephin promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. Persephin is a ligand for the RET receptor tyrosine kinase.
Bioactivity Assay:TT cell proliferation; ED50 =20 ng/mL; Bioactivity =5.0 x 10^4 units/mg