NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® C18 Pyramid
Octadecyl modification with polar endcapping, USP L1
Key features:
- Stable in 100 % aqueous mobile phase systems
- Special phase with polar endcapping
- Interesting polar selectivity features
- Excellent base deactivation; suitable for LC/MS due to low bleeding characteristics
Technical characteristics:
- Pore size 110 Å
- Particle sizes 1.8 µm (UHPLC), 3 μm and 5 μm • 7 and 10 μm particles for preparative purposes on request
- pH stability 1–9
- Carbon content 14 %
Recommended application: Analgesics, penicillin antibiotics, nucleic acid bases, water-soluble vitamins, complexing agents, organic acids