Antigen: fusion protein amino acids 2-77 of human KCNQ4
Host: mouse, clone S43-6
Isotype: IgG1
Cross Reactivity: (+) human, mouse, and rat KCNQ4
Application(s): ICC, IP, and WB
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and is activated by retigabine, a novel anti-convulsant drug.