Primary Polyclonal

Antigen: synthetic peptide from human histone H2A amino acids 1-15 and 81-96 Host: rabbit Cross Reactivity: (+) human and mouse histone H2A Application(s): ELISA and WB

A polyclonal anti-choleragenoid from goat that is suitable for use in toxin neutralization and binding assays or for immunohistochemical studies in conjunction with the cholera toxin B subunit.

Antigen: nitrotyrosine-containing synthetic peptide Host: rabbit Cross Reactivity: (+) nitrotyrosine (species independent), less than 10% reactivity with chlorotyrosine; (−) synthetic peptide containing unmodified tyrosine Application(s): WB Cayman’s nitrotyrosine (peptide) polyclonal...

Antigen: human SET7/9 amino acids 131-145 and 336-352 Host: rabbit Cross Reactivity: (+) human and mouse SET7/9 Application(s): WB SET7/9 is a histone specific HMTase that methylates histone H3 lysine 4.

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser845 of GluR1 Host: rabbit Cross Reactivity: (+) rat GluR1 Application(s): IHC and WB The AMPAR are comprised of four distinct GluR subunits designated (GluR1-4), which play key roles in virtually all excitatory...

Antigen: human HMGB1 amino acids 100-150 Host: rabbit Cross Reactivity: (+) human, bovine, chicken, mouse, New World monkey, and rat HMGB1 Applications: FC, IHC (paraffin-embedded tissue), and WB HMGB1 is a necessary and sufficient mediator of inflammation during sterile and infection-associated...

Antigen: human TX synthase amino acids 359-377 Host: rabbit Cross Reactivity: (+) human, mouse, porcine, and rat TX synthase Application(s): IHC and WB TX synthase catalyzes the conversion of PGH2 to TXA2, which is a potent vasoconstrictor and inducer of platelet aggregation.

Antigen: human SPHK 1 amino acids 264-274 Host: rabbit Cross Reactivity: (+) human and mouse SPHK 1, expected to react with rat SPHK 1 Application(s): WB and ICC SPHK 1 catalyzes the phosphorylation of sphingosine to S1P. This reaction plays an important role in determining cell proliferation versus...

Antigen: peroxynitrite-treated KLH Host: rabbit Application(s): WB The presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. Nitrotyrosine has been shown to be present in proteins from a variety of clinical conditions including artherosclerotic lesions of...

Immunogen: human CMKLR1 amino acids 358–371 Host: rabbit Cross Reactivity: (+) human, monkey, mouse, and rat CMKLR1 Application(s): FC, IF, and WB CMKLR1 is a GPCR relevant to the cellular chemotaxis of dendritic cells and macrophages. Chemerin, or TIG2, and Resolvin E1 are ligands for this...

Antigen: native bovine ubiquitin conjugated to KLH Host: rabbit Cross Reactivity: (+) human, monkey, mouse, rat, hamster, rabbit, guinea pig, bovine, porcine, canine, pvine, chicken, Xenopus, yeast, Drosophila, and Rainbow Trout ubiquitin Application(s): WB, IP, and ChIP Ubiquitin functions to clear...

Peptide Sequence: human hematopoietic type PGD synthase amino acids 30-41 (EDHRIEQADWPE) To be used in conjunction with Cayman’s hematopoietic type PGD synthase polyclonal antibody (Catalog No. 160013) to block protein-antibody complex formation during analysis for hematopoietic type PGD...

Peptide Sequence: CRTH2/DP2 protein amino acids 2-21 To be used in conjunction with Cayman’s CRTH2/DP2 Receptor (N-Term) polyclonal antibody (Item No. 10004886) to block protein-antibody complex formation during immunochemical analysis of CRTH2/DP2

Antigen: human caspase-9 amino acids 299-318 Host: rabbit Application(s): WB Caspase-9 is activated by granzyme B, CPP32, or by binding Apaf-1. Activated caspase-9 cleaves and activates caspase-3, playing a central role in cell death induced by a wide variety of apoptosis inducers including...

Antigen: mouse COX-2 amino acids 584-598 Host: rabbit Cross-Reactivity: (+) human, macaque monkey, mouse, ovine, and rat COX-2; (−) COX-1 (all species); expected to react with bovine and canine COX-2 Application(s): IHC (formalin-fixed paraffin-embedded tissue) and WB

Antigen: human GPR120 amino acids 364-375 Host: rabbit Cross Reactivity: (+) human GPR120 Application(s): ELISA, ICC, and WB

Peptide Sequence: amino acids 221-235 (VYGGKEARTEEMKWR) To be used in conjunction with Cayman’s mPGE synthase-2 polyclonal antibody (Catalog No. 160145) to block protein-antibody complex formation during analysis for microsomal PGE synthase-2.

Antigen: rat FAAH amino acids sequence 561-579 Host: rabbit Cross Reactivity: (+) human, ferret, mouse, and rat FAAH; other species not tested Application(s): WB

Antigen: mouse TLR12 amino acids 911-926 Host: rabbit Cross Reactivity: (+) mouse and rat TLR12 Application(s): FC (intracellular) and WB TLR12 displays a distinct pattern of expression in macrophages, liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.

Immunogen: synthetic peptide from the N-terminal region of human IP receptor Host: rabbit Species Reactivity: (+) human IP receptor Application(s): WB The IP receptor is a GPCR that mediates the action of PGI2. It participates in signal transduction of the pain response, cardioprotection, and...

Antigen: 5,5-dimethyl-2-(8-octanoic acid)-1-pyrroline N-oxide coupled to ovalbumin Host: rabbit Cross-reactivity: species independent Applications: WB, ICC, and ELISA Proteins with endogenous peroxidase activity are susceptible to forming radical adducts. Immunodetection of spin trap products allows...

Antigen: human nNOS amino acids 1422-1433 Host: rabbit Cross Reactivity: (+) rat and human nNOS; (−) iNOS and eNOS Application(s): ICC, IHC, IP, and WB NOS catalyzes the oxidation of arginine to nitric oxide and citrulline. nNOS is a soluble enzyme found in brain, the peripheral nervous system...

Immunogen: peptide from the C-terminal region of mouse COX-2 Host: rabbit Cross-reactivity: (-) COX-1 (all species) Species reactivity: (+) human, guinea pig, monkey, mouse, ovine, rabbit, and rat COX-2 Applications: WB and IHC

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1252 of the human NMDA Receptor NR2B Subunit Host: rabbit Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor...