Primary Polyclonal

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser133 of rat CREB Host: rabbit Cross-reactivity: (+) rat CREB Application: WB CREB is one of the best characterized stimulus-induced transcription factors. This transcription factor is a component of intracellular...

Antigen: human LCAT protein amino acids 132-143 Host: rabbit Cross Reactivity: (+) human, mouse, porcine, and bovine LCAT Application(s): WB LCAT catalyzes the fatty acid transfer from the sn-2 position of phosphatidylcholine (lecithin) to cholesterol and to a lesser degree to other acceptor...

Antigen: human erythrocyte TXB2 11-dehydrogenase Host: rabbit Cross Reactivity: (+) human, porcine, and ovine TXB2 11-dehydrogenase Application(s): WB TXB2 11-dehydrogenase catalyzes the conversion of TXB2 to 11-dehydro TXB2.

Antigen: human AIF amino acids 151-180 Host: rabbit Cross Reactivity: (+) human, rat, and mouse AIF; other species not tested Application(s): WB AIF is a highly conserved mitochondrial protein with roles in redox-biochemistry and apoptosis.

Antigen: human CysLT1 receptor C-terminal amino acids 318-337 Host: rabbit Cross Reactivity: (+) human and mouse CysLT1 receptor Application(s): FC The CysLT1 receptor binds LTD4, LTC4, and LTE4, playing a major role in

Antigen: human S1P3 amino acids 12-25 Host: rabbit Cross Reactivity: (+) human, mouse, and rat S1P3 Application(s): ICC and WB S1P3 is one of five GPCRs that are activated by S1P. It couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and...

Antigen: human eNOS amino acids 1186-1203 Host: rabbit Cross Reactivity: (+) bovine and human eNOS; (−) iNOS and nNOS Application(s): IP and WB eNOS catalyzes the formation of NO from L-arginine in many cell types including vascular endothelium, bronchiolar epithelium, cardiac myocytes,...

Antigen: human lysophosphatidic acid 1 (LPA1) amino acids 342-359 Host: rabbit Cross Reactivity: (+) bovine, human, mouse, ovine, and rat LPA1 Application(s): ICC and WB LPA1 is a GPCR that couples with three types of G proteins, Gi/o, Gq, and G12/13 to induce a range of cellular responses including...

Immunogen: peptide from the N-terminal region of human NAPE-PLD Host: rabbit Species Reactivity: (+) human, mouse, rat, and bovine NAPE-PLD Application(s): WB NAPE-PLD catalyzes the hydrolysis of NAPE to form N-acylethanolamines (NAEs), which are involved in diverse biological processes such as...

Peptide sequence: human cPGE synthase amino acids 58-67 (CIDPNDSKHK) To be used in conjunction with Cayman’s cPGEsynthase polyclonal antibody (Catalog No. 160150) to block protein-antibody complex formation during analysis for cPGE synthase.

Antigen: Human GPR35 amino acids 295-304 Host: rabbit Species Reactivity: (+) Human, mouse, and porcine GPR35 Application(s): IHC (paraffin-embedded tissue) and WB GPR35 ligands include kynurenic acid and zaprinast. Multiple isoforms of this receptor have been reported and GPR35 mRNAs were detected...

Antigen: human EP4 receptor C-terminal amino acids 459-488 Host: rabbit Cross Reactivity: (+) human, mouse, ovine, and rat EP4 receptors; (−) EP1, EP2, and EP3 receptors Application(s): ICC, IHC, and WB Binding of PGE2 to the EP4 receptor causes an increase in intracellular cyclic AMP and...

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3β Host: rabbit Cross Reactivity: (+) rat GSK3β; expected to react with human, bovine, canine, chicken, mouse, non-human primate, Xenopus, and zebrafish GSK3β Application(s): WB GSK3 is a...

Peptide affinity-purified IgG Immunogen: peptide from the C-terminal region of human MBOAT5 Host: rabbit Species Reactivity: (+) human Application(s): FC and IF

Antigen: human ARAP2 within the region of amino acids 1,670-1,720 Host: rabbit Cross Reactivity: (+) human ARAP2 Application(s): IHC and WB ARAP2 is a PIP3-dependent GTPase-activating protein that binds to RhoA-GTP, and modulates actin cytoskeleton remodeling by regulating ARF and RHO family...

Antigen: human PINK1 amino acids 484-504 Host: rabbit Cross Reactivity: (+) human, mouse, and rat PINK1 Application(s): WB and IHC (paraffin-embedded sections) PINK1 was first identified when studying the tumor-suppressive function of the PTEN signaling pathway and is thus believed to be involved in...

Antigen: human Trx1 Host: goat Application(s): ELISA, IHC, and WB

Antigen: human recombinant MCAD Host: rabbit Cross Reactivity: (+) human, porcine, ovine, and mouse MCAD; other species not tested Application(s): WB; other applications not tested MCAD is a mitochondrial enzyme that catalyzes the first step in the β-oxidation of fatty acids. Its expression is...

Peptide Sequence: human LPA1 amino acids 342-359 To be used in conjunction with Cayman’s LPA1 polyclonal antibody (Catalog No. 10005280) to block protein-antibody complex formation during immunochemical analysis of LPA1.

Antigen: human endothelial lipase amino acids 19-32 Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and ovine endothelial lipase Application(s): IHC and WB EL is a major genetic determinant for the concentration, structure, and metabolism of HDL, which protects against...

Antigen: amino acids around phospho-Ser392 Host: rabbit Application(s): WB Nearly 50% of human tumors have mutated or non-functional p53. p53 amino acid residues can be modified by phosphorylation and acetylation. In vivo phosphorylation of p53 residues alters signal transduction events that warrant...

Antigen: synthetic peptide from the human mPGES-2 sequence conjugated to KLH amino acids 221-235 Host: rabbit Cross-Reactivity: (+) human, mouse, rat, ovine, bovine, and Cos-7 (African green monkey) mPGES-2; suspected positive with macaque but not yet tested (−) mPGEs-1, cPGES Application: WB

Antigen: human GPR31 amino acids 288-298 Host: rabbit Cross Reactivity: (+) human GPR31 Application(s): ELISA, ICC, and WB

Antigen: human PTEN amino acids 254-270 Host: rabbit Cross Reactivity: (+) human, mouse, chimpanzee, canine, and rat PTEN Application(s): WB and IHC (paraffin-embedded sections) PTEN dephosphorylates proteins and lipids such as Akt and PIP3 and therefore functions as a key regulatory enzyme in a...