Life Science Reagents

GPR109A is a high affinity receptor for nicotinic acid (niacin) and is a member of the nicotinic acid receptor family of G protein-coupled receptors (the other identified member being GPR109B). GPR109A is a G_i/o protein-coupled receptor with high affinity for nicotinic acid. In GPR109A...

NucView® 488 Caspase-3 Substrate is a novel fluorogenic caspase substrate for real-time detection of caspase-3/7 activity in live cells. In apoptotic cells, the substrate is cleaved to release a DNA dye that stains the nucleus with bright green fluorescence. 1 mM in PBS, 100 uL.

The rabbit immune system generates antibody diversity and optimizes affinity. GenScript utilizes MonoRab™ technology to generate the high affinity and specificity monoclonal rabbit antibodies. MonoRab™ DYKDDDDK Tag Antibody [FITC], mAb, Rabbit specific to DYKDDDDK tags placed at...

CCL25 (thymus expressed chemokine) is a novel CC chemokine that is distantly related (approximately 20% amino acid sequence identity) to other CC chemokines. Mouse CCL25 cDNA has also been cloned and shown to encode a 144 aa protein that exhibits 49% aa sequence identity to human CCL25. The...

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its...

KE00137 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The ORM1 ELISA kit is to be used to detect and quantify protein levels of endogenous ORM1. The assay recognizes human ORM1. An antibody specific for ORM1 has been pre-coated onto the microwells. The ORM1 protein...

eStain L1 Gel Holder

CD4 is a coreceptor with T cell receptor on T lymphocytes to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. 25%-65% human lymphocytes are CD4 positive. Human CD4 Magnetic Beads are used for isolation or depletion of human CD4 T lymphocytes from...

Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by...

KE00075 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The PD1 ELISA kit is to be used to detect and quantify protein levels of endogenous PD1. The assay recognizes human PD1. An antibody specific for PD1 has been pre-coated onto the microwells. The PD1 protein in...

Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of hematological cancers and autoimmune diseases. When Rituximab binds to CD20 on the surface of normal and malignant B cells, natural killer (NK) cells is...

Drop-n-Stain EverBrite™ Mounting Medium is wet-set antifade mounting medium supplied in a convenient dropper bottle. EverBrite™ protects a variety of fluorescent dyes from photobleaching, and is compatible with cyanine-based dyes like Cy® dyes and Alexa Fluor® 647.

Adalimumab, sold under the trade name Humira among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis. Adalimumab is a...

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the ß-defensins by the pairing of their three disulfide bonds. To date, four human ß-defensins have been...

Interleukin-22(IL-22) belongs to a group of cytokines called the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26) which are a class of potent mediators of cellular inflammatory responses. It shares use of IL-10R2 in cell signaling with other members of this family, such...

Texas Red®-DHPE (N-(Texas Red sulfonyl)-1,2-dihexadecanoyl-snglycero-3-phosphoethanolamine, triethylammonium salt) is a rhodamine-labeled glycerophosphoethanolamine lipid. DHPE conjugates of rhodamine dyes have been used as fluorescence energy acceptors in combination with NBDPE as the donor in...

Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets....

High quality streptavidin biotin binding protein conjugated to horseradish peroxidase (HRP).

Sharing 79% sequence identity with human Tumor Necrosis Factor-alpha (hTNF-a), mouse Tumor Necrosis Factor-alpha (mTNF-a) is a cytokine mainly expressed by immune cells [1] . A type II transmembrane protein, TNF-a is further proteolytically processed to a soluble form [2] . The trimeric active TNF-a...

Fast Probe Master Mix is formulated for conducting real-time PCR using oligo-based probes such as TaqMan® or MGB probes. The master mix contains buffer, dNTPs, MgCl2 and our superior hotstart enzyme Cheetah™ Taq. Cheetah™ Taq is a chemically modified hotstart Taq which can be fully activated in 2...

FDP (fluorescein diphosphate, tetraammonium salt, high purity) is the most sensitive fluorogenic alkaline phosphatase substrate. It is also an excellent substrate for protein tyrosine phosphatase (PTPase) and thus the substrate of choice in the high throughput screening (HTS) for PTPase inhibitor....

Interleukin 9, also known as IL9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine...

Methylene Blue (MB) is a commonly used redox indicator in nucleic acid research. MB-Maleimide can be used to label molecules containing free thiol groups.

Single donor specimens collected from donors prior to and continuing through disease progression.