UM-SCC-17A is a unique head and neck squamous carcinoma cell line isolated from the primary laryngeal carcinoma of a 48-year old female patient who failed to respond to radiation therapy. The tumor persisted and metastasized to the neck, from where the UM-SCC-17B cell line was derived from. The patient achieved long-term remission after surgery . UM-SCC-17A is negative for HPV-16, HPV-18, Hepatitis A, B, C, HIV-1 & 2 viruses and grows as tightly packed colonies or islands. UM-SCC-17A was established at the University of Michigan with written informed consent obtained from the patient and with the approval of the study by the Medical School Institutional Review Board.
Synonyms: UMSCC17A HNSCC Head and neck squamous cell carcinoma cell line H&N squamous cell carcinoma cell line
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