Widely used as a biological buffer (absorbance: <=0.03 at 260 nm; <=0.02 at 280 nm). Useful in the pH range of 7.0-9.0. Has a pKa of 8.1 at 25C.
Synonyms: Tris(hydroxymethyl)aminomethane; tris(Hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Tris base; Trometamol
Molecular Formula: C4H11NO3
Molecular Weight: 121.14
Linear Structural Formula: NH2C(CH2OH)3
MDL Number: MFCD00004679
Purity: >=99% (perchloric acid titration)
Melting Point: 167-172 C (lit.)
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