Trifluoromethanesulfonic acid, reagent grade, 98%

Synonyms: TFMSA; Triflic acid

CAS Number: 1493-13-6

Formula: CHF3O3S

Formula Weight: 150.08

Linear Formula: CF3SO3H

MDL No.: MFCD00007514

Purity: 0.98

Boiling Point: 162 C(lit.)

Density: 1.696 g/mL at 25 C(lit.)

Refractive Index: n20/D 1.327(lit.)

Beilstein Registry Number: 1812100

EC Number: 216-087-5

UNSPSC Code: 12352100

General description: Trifluoromethanesulfonic acid is the strongest monoprotic organic acid. It has been synthesized by the oxidation of bis(trifluoromethylthio)mercury with aqueous hydrogen peroxide. It undergoes complete dissociation in basic solvents such as dimethyl sulfoxide, dimethylacetamide and dimethylformamide. Its dissociation in non-aqueous solvents has been studied by conductometry. On mixing trifluoromethanesulfonic acid with HNO3, it forms nitronium trifluoromethane sulfonate, which is an excellent nitrating reagent.

Application: Deglycosylation agent

Application: Trifluoromethanesulfonic acid may be used as an initiator for the cationic polymerization of styrene, hexamethylcyclotrisiloxane and L,L-dilactide.

Application: Trifluoromethanesulfonic acid is a versatile reagent, employed as catalyst for the following studies:. Friedel-Crafts acylation of aromatic compounds with methyl benzoate.. Addition reaction of dialkyl disulfides to terminal alkynes.. Synthesis of a single cyclic tetrasiloxane containing propylammonium trifluoromethanesulfonate and methyl side-chain groups (Am-CyTS).. Preparation of starting reagents for the synthesis of fluorinated 2,5-substituted 1-ethyl-1H-benzimidazole derivatives.. Synthesis of aryl triflates, the lactonization of alkenoic acids, and the formation of E-alkenes.