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MilliporeSigma

SIGMA G 418 disulfate salt solution, 50mg/mL in H2O, sterile-filtered, BioReagent, suitable for cell culture

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SIGMA G 418 disulfate salt solution, 50mg/mL in H2O, sterile-filtered, BioReagent, suitable for cell culture

Chemical structure: aminoglycoside

Synonyms: Antibiotic G418

Molecular Formula: C20H40N4O10 · 2H2SO4

Molecular Weight: 692.71

Linear Structural Formula: C20H40N4O10 · 2H2SO4

MDL Number: MFCD00058314

Storage: 2-8C

Application: G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 mug/mL or less while animal cells may require 300-500 mug/mL.

Biochem Physiol Actions: Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.

Biochem/physiol Actions: Mode of Action: Blocks polypeptide synthesis and inhibits elongation in the selection and maintenance of eucaryotic cells stably transfected with neomycin resistance gene

Empirical Formula (Hill Notation): C9H13NO

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Product Detail
Thomas No.
C980W88
Mfr. No.
G8168-10ML
Description
G 418 disulfate salt solution, 50mg/mL in H2O, sterile-filtered, BioReagent, suitable for cell culture, 10 mL
CAS Number
108321-42-2
Packaging Size
10 mL
list price/quantitytotal
$0.00
Thomas No.
C980W89
Mfr. No.
G8168-100ML
Description
G 418 disulfate salt solution, 50mg/mL in H2O, sterile-filtered, BioReagent, suitable for cell culture, 100 mL
CAS Number
108321-42-2
Packaging Size
100 mL
list price/quantitytotal
$0.00
Thomas No.
CHM01S167
Mfr. No.
G8168-50ML
Description
G8168-50ML G 418 disulfate salt solution 50 mg/mL in H2O, 0.1 mum filtered, BioReagent, suitable for cell culture
CAS Number
108321-42-2
Packaging Size
list price/quantitytotal
$0.00
$0.00 (0 Items)
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