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An ALK1 and ALK2 inhibitor (IC50s = 1.8 and 1.1 nM, respectively) that can prevent BMP4-induced SMAD1/5/8 pathway activation in vitro (IC50 = 100 nM) without affecting TGF-β signaling; less selective for ALK3, 4, 5, and 6 subtypes and the type II BMP receptor ActRIIA (IC50s = 34.4, 302, 321, 6.4, and 220 nM, respectively).

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Product Detail
Thomas No.
C817X07
Mfr. No.
16678-1
Description
K02288-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X08
Mfr. No.
16678-5
Description
K02288-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X09
Mfr. No.
16678-10
Description
K02288-10 mg
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X10
Mfr. No.
16678-50
Description
K02288-50 mg
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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