IFN alpha 2a, Interferon alpha 2a, human: Human Interferon-α2a
At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Source: Escherichia coli.
Molecular Weight: Approximately 19 kDa, a single non-glycosylated polypeptide chain containing 165 amino acids.
Quantity: 20ug/100ug/1mg
Purity: >97% by SDS-PAGE and HPLC analyses.
Biological Activity: Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay was found to be no less than 1.0 x 108 IU/mg.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation: Lyophilized from a 0.2mm filtered solution in PBS, pH 7.4.
Endotoxin: Less than 1EU/mg of rHuIFN-α2a as determined by LAL method.