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MilliporeSigma

IN-1130 >=98% (HPLC)

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IN-1130 >=98% (HPLC)

Synonyms: 3-[[5-(6-Methyl-2-pyridinyl)-4-(6-quinoxalinyl)-1H-imidazol-2-yl]methyl]-benzamide; IN 1130

Molecular Formula: C25H20N6O

Molecular Weight: 420.47

Linear Structural Formula: C25H20N6O

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: IN-1130 is a potent inhibitor of the activin receptor-like kinase ALK-5 (Type 1 TGF1beta recptor). The compound inhibits phosphorylation of Smad-2 with an IC50 of 36 nM. IN-1130 inhibits renal fibrosis, and also reduces tumor volume in prostate tumor xenografts in murine models.

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Product Detail
Thomas No.
CHM02Y661
Mfr. No.
SML1403-5MG
Description
SML1403-5MG, IN-1130 >=98% (HPLC)
CAS Number
868612-83-3
list price/quantitytotal
$0.00
Thomas No.
CHM02Y662
Mfr. No.
SML1403-25MG
Description
SML1403-25MG, IN-1130 >=98% (HPLC)
CAS Number
868612-83-3
list price/quantitytotal
$0.00
$0.00 (0 Items)
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