Synonyms: 2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]acetonitrile
Molecular Formula: C13H8ClN5OS
Molecular Weight: 317.75
Linear Structural Formula: C13H8ClN5OS
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: HS56 is a highly selective and potent dual Pim/DAPK3 inhibitor that significantly reduces contractile intensity and phosphorylation levels of myosin light chain (LC20) in rat caudal arterial smooth muscle strips. HS56 decreases blood pressure in spontaneously hypertensive mice without affecting heart rate.