Synonyms: N-[4-[3-[[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]amino]phenyl]-2-thiazolyl]-acetamide
Molecular Formula: C23H22N4O3S2
Molecular Weight: 466.58
Linear Structural Formula: C23H22N4O3S2
MDL Number: MFCD30377202
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: HA15 is a selective ligand of BiP/GRP78/HSPA5 chaperone that increases ER stress, leading to autophagic and apoptotic cell death in varies cancer cell lines including melanoma cells. HA15 inhibits inhibit the ATPase activity of BiP. HA15 inhibits tumor development in mice injected with A375 melanoma cells.