Synonym: FITC–Dextran, FITC-Dextran 70
MDL Number: MFCD00131092
Other Notes
Internalisation of FITC and FITC-dextran by suspension cultured plant cells; In the study of fluid pinocytosis in leukocytes.
Application
Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
Fluorescein isothiocyanate–dextran (FITC-Dextran 70) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-Dextran 70 may be used to study the capacity, selectivity and efficiency of encapsulation and release by drug delivery vehicles.
Assay: (FITC:Glucose = 1:250)
Mol. Wt.: average mol wt 70,000
Extent of Labeling: ~0.004 mol/mol FITC glucose
Solubility: H2O: soluble50 mg/mL, hazy, orange to very deep orange
Fluorescence: λex 492 nm; λem 518 nm in ethanol
Storage Temp.: 2-8°C