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MilliporeSigma

EU1794-4 >=98% (HPLC)

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Synonyms: 2-[[(2-Amino-4,5-dihydro-4-oxo-5-thiazolyl)acetyl]amino]-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxylic acid ethyl ester; 2-[[(2-Imino-4-oxo-1,3-thiazolidin-5-yl)acetyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester; EU 1794-4; Ethyl 2-(2-(2-imino-4-oxothiazolidin-5-yl)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

Molecular Formula: C16H19N3O4S2

Molecular Weight: 381.47

Linear Structural Formula: C16H19N3O4S2

MDL Number: MFCD01831186

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: EU1794-4 is an N-methyl-d-aspartate (NMDA) receptor (NMDAR) allosteric modulator that prevents large degree receptor activation in the presence of high level Glu/Gly (IC50/Emax = 2.2 muM/32%/GluN2A, 2.6 muM/67%/GluN2B, 0.42 muM/52%/GluN2C, 0.36 muM/51%/GluN2D with Glu/Gly = ECmax = 100/30 muM using xenopus oocytes co-expressing rat GluN1 and respective GluN2 subtype), while augmenting receptor activation at low level Glu/Gly (EC50/Emax = 3.9 muM/500%/GluN2A, 4.3 muM/210%/GluN2B, 15 muM/220%/GluN2C with Glu/Gly = 1/0.3 muM; 14 muM/540%/GluN2D with Glu/Gly = 300/9 nM).

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Product Detail
Thomas No.
CHM03P840
Mfr. No.
SML2412-5MG
Description
SML2412-5MG, EU1794-4 >=98% (HPLC)
CAS Number
305373-14-2
list price/quantitytotal
$0.00
Thomas No.
CHM03P841
Mfr. No.
SML2412-25MG
Description
SML2412-25MG, EU1794-4 >=98% (HPLC)
CAS Number
305373-14-2
list price/quantitytotal
$0.00
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