Synonyms: 5'-S-[2-[[(Ethylamino)carbonyl]amino]ethyl]-5'-thio-adenosine
Molecular Formula: C15H23N7O4S
Molecular Weight: 397.45
Linear Structural Formula: C15H23N7O4S
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: DS-437 is an analog of S-adenosyl methionine (SAM ), which inhibits protein arginine methyltransferases PRMT5 and PRMT7 (IC50 5.9 and 6 muM) with little interaction against a panel of 30 other human methyltransferases.
Other Notes: DS-437 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the DS-437 probe summary on the Chemical Probes Portal website.