Antigen: mouse DP1 receptor N-terminal amino acids 2-21
Host: rabbit
Cross Reactivity: human, mouse, and rat DP1 receptors
Application(s): IHC and WB
DP1 receptor is one of two receptor isoforms for PGD2, a major COX metabolite of arachidonic acid. As a GPCR, the receptor primarily couples to Gs to increase cAMP, but also transiently increases Ca2+, apparently through the cAMP pathway.