Synonyms: 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-beta-Dglucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-alpha-D-mannopyranosyl-N15-methyl- Ristomycin A aglycone; BI 397; BI-397; BI397; MDL 63,397; MDL 63397; MDL-63,397; MDL-63397; MDL63,397; MDL63397; Ristomycin A aglycone; VER 001; VER-001; VER001
Molecular Formula: C88H100Cl2N10O28
Molecular Weight: 1816.69
Linear Structural Formula: C88H100Cl2N10O28
Purity: >=90% (HPLC)
Storage: -20C
Biochem Physiol Actions: Dalbavancin is a semisynthetic, vancomycin class lipoglycopeptide with antibacterial activity against a variety of gram-positive pathogens, including methicillin-resistant S. aureus & S. epidermidis (MRSA & MRSE), but not gram-negative or vancomycin-resistant enterococci that possess VanA gene. Similar to vancomycin and other class members (e.g. teicoplanin, telavancin, ramoplanin, and ritavancin), dalbavancin disrupts bateria cell wall formation and cell membrane integrity by targeting the D-alanyl-D-alanyl residues on the growing peptidoglycan chains, blocking transpeptidation and peptidoglycan elongation.