A fungal metabolite possessing potent immunosuppressive properties, inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin. Also, Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα, and blocks cytochrome c release from mitochondria. For research use.
Molecular Weight : 1202.61
Molecular Formula : C62H111N11O12
CAS : 59865-13-3
Storage : 4°C