Chondroitinase ABC is a lyase with specificity toward chondroitin sulfates and dermatan sulfates - with some minor activity toward hyaluronan. This recombinant version only contains the endolytic chondroitinase, meaning it will not digest the non-reducing ends of proteoglycan substrates. It targets beta-(1,4)-linkages between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid. The product of digestion is a mixture of Delta 4-unsaturated tetra- and di-saccharides.
Storage: -70C
Application:
•Degradation of Chondroitin sulfate-containing tissue such as extracellular matrices and cartilage
•Neural regeneration research
•Eliminative degradation of all forms of Chondroitin sulfate: A, B and C
•Quantitation of glucosaminoglycans (mucopolysaccharides)
Other Notes: This product is for R&D use only. Not for drug, household, or other uses. Please consult the SafetyData Sheet for information regarding hazards and safe handling practices.