Purity: >95% (TLC)
Storage: -20C
Biochem Physiol Actions: Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM) (1). Protects cells against NAC-amyloid-induced cell death (2). Cell permeable. MW=260.4. Purity ?95% by TLC. Formulated as a lyophilized powder. May be dissolved in DMSO (>25 mg/mL) or DMF (30 mg/mL). Stable desicated as supplied at ambient temperature for up to 2 years, or in solution at -20C for up to 2 months.