C19orf59 is also called MCEMP1 (mast cell-expressed membrane protein 1) is a single pass transmembrane protein. It is composed of 186 amino acids, and is predominantly expressed in mast cells and monocytes. This gene maps to human chromosome 19p13.3, and has seven exons. It resides in the plasma membrane, and has a cytoplasmic N-terminal and an extracellular C-terminal.
Synonyms: Anti-C19orf59; Anti-MGC132456
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: C19orf59 is up-regulated in patients with ischemic stroke.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC