Synonyms: Anti-Adapter protein GRID antibody produced in rabbit; Anti-GADS protein antibody produced in rabbit; Anti-GRB-2-like protein antibody produced in rabbit; Anti-GRB2-related adapter protein 2 antibody produced in rabbit; Anti-GRB2L antibody produced in rabbit; Anti-GRBLG antibody produced in rabbit; Anti-GRBX antibody produced in rabbit; Anti-Grf-40 antibody produced in rabbit; Anti-Grf40 adapter protein antibody produced in rabbit; Anti-Growth factor receptor-binding protein antibody produced in rabbit; Anti-Hematopoietic cell-associated adapter protein GrpL antibody produced in rabbit; Anti-P38 antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: GRB2-related adapter protein 2 is a protein encoded by the GRAP2 gene in humans. It is referred as P38, GADS, GRID, GRPL, GrbX, Mona, GRB2L, GRBLG, Grf40 and GRAP-2. It is involved in tyrosine kinase signaling in hematopoietic cells as well as plays a tissue-specific role as an inhibitor of RET mitogenic signaling. Its expression is restricted to hematopoietic cells and plays an important role in intracellular signaling in T cells, monocytic cells and platelets.
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