Synonyms: G protein, beta-3 subunit; GTP-binding regulatory protein beta-3 chain; Guanine nucleotide binding protein (G protein), beta polypeptide 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
Storage: -20C
UNSPSC Code: 12352203
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General description: The guanine nucleotide binding protein +¦3 (GNB3) gene is composed of 11 exons and 10 introns. It is the 3 subunit of heterotrimeric G-proteins located on human chromosome 12p13.
Biochem/physiol Actions: Guanine nucleotide binding protein 3 (GNB3) is involved in the conversion of external receptor activation signals into intracellular signals and it plays an important role in signal transduction pathways. It modulates and associates with favorable antidepressant response. GNB3 takes part in a variety of cellular processes like G protein-coupled receptor signaling.
Immunogen: Peptide with sequence SGHDNRVSCLGVT, from the internal region of the protein sequence according to NP_002066.1, NP_067642.1
Physical form: Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
RIDADR: NONH for all modes of transport
WGK Germany: 2
R Codes: 22
IOD Codes: Xn