XPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XPhos Pd G3 is an excellent reagent for Suzuki cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
Synonyms: (2-Dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate; XPhos-G3-Palladacycle; XPhos-Pd-G3
Molecular Formula: C46H62NO3PPdS
Molecular Weight: 846.45
Linear Structural Formula: C46H62NO3PPdS
MDL Number: MFCD22666043
Purity: 98%
Melting Point: 146-151 C (decomposition)
Application: XPhos Pd G3 may be used in the following reactions:
•Cyanation reaction of heterocyclic halides.
•Coupling of heteroaryl chlorides with polyfluoroaryl zinc reagents.
•Coupling of 2,6-difluorophenylboronic acid with (hetero)aryl chlorides.
Hazard statements: H412
Precautionary statements: P273
Risk Statements (Europe): 52/53
Safety Statements (Europe): 61