XantPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XantPhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
Synonyms: [(4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate
Molecular Formula: C52H45NO4P2PdS
Molecular Weight: 948.35
Linear Structural Formula: C52H45NO4P2PdS
MDL Number: MFCD22572675
Purity: 95%
Melting Point: 164-167 C (decomposition)
Application: XantPhos Pd G3 may be used in the following processes:
•Negishi cross-coupling reaction during the synthesis of palmerolides.
•Aminocarbonylation of heteroaryl bromides with carbon monoxide (CO) in the presence of triethylamine.
•Coupling between polyglycosyl thiols and aglycon halides by C-S bond formation.