Synonym(s): (Bromodifluoromethyl)phosphonic acid diethyl ester
Formula: BrCF2P(O)(OC2H5)2
Formula Weight: 267.01
CAS No.: 65094-22-6
Purity: 96%
Density: 1.503g/mLat 25°C(lit.)
Application: Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps
• P-C bond cleavage on basic hydrolysis
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)
Packaging: 5 g in glass bottle
Boiling Point: 40-41°C/0.05mmHg(lit.)
Refractive Index: n20/D 1.417(lit.)