Life Science Reagents

The H1 histamine receptor is expressed primarily in the lungs, vasculature, and brain. The H1 mediates the contraction of smooth muscles, neurotransmission in the central nervous system, the release of catecholamine from adrenal medulla, and increases in capillary permeability due to contraction of...

KE00294 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The EGFR ELISA kit is to be used to detect and quantify protein levels of endogenous EGFR. The assay recognizes human EGFR. An antibody specific for EGFR has been pre-coated onto the microwells. The EGFR protein...

CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes and is used as a marker for these cells. It acts as a coreceptor for T cell receptor and functions to recognize MHC –I antigens. 10%-30% human lymphocytes are CD8 positive. Human CD8 Magnetic Beads Kit is used for isolation or...

Methylene Blue (MB) is a commonly used redox indicator in nucleic acid research. MB-methyltetrazine may be used to label TCO (trans-cyclooctene) tagged molecules via a copper-free reaction.

Oxazole Gold, also known as SYBR® Gold, is a cell-permeant, green fluorescent DNA/RNA dye. It can be used to stain ssDNA, RNA, or dsDNA agarose or PAGE gels for UV or blue LED detection. It is the most sensitive gel stain available for single-stranded and denatured DNA/RNA. 10,000X in DMSO, 500 uL.

V5 epitope tag (GKPIPNPLLGLDST) is derived from a small epitope which presents on the P and V proteins of the paramyxovirus of simian virus 5 (SV5). GenScript THE ™ V5 Tag Antibody [Biotin], mAb, Mouse is THE ™ V5 Tag Antibody (A01724) conjugated with biotin. The conjugated antibody is...

Evaluate the performance of nucleic acid tests for determination of the presence of targeted viral, bacterial, and parasitic nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C...

BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an...

Single donor specimens collected from donors prior to and continuing through disease progression.

Coelenterazine h (2-(4-Dehydroxy) coelenterazine) is a synthetic derivative of coelenterazine. The luminescence intensity of its aequorin complex is more than 10 times higher than that of the aequorin formed from native coelenterazine. Also see water soluble Aquaphile Coelenterazine h. Yellow solid...

Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in the lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF and receptor binding to FGFR2-IIIb. However, while KGF...

6-FAM, SE (full name: 6-Carboxyfluorescein, succinimidyl ester, single isomer) is the amine-reactive form of 6-carboxyfluorescein single isomer. &lamba;_Ex/&lamba;_Em (pH 9) = 495/519 nm Yellow-orange solid soluble in DMF or DMSO Store at -20°C and protect from light...

Eotaxin also called CCL11 is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-gamma stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and along Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil...

NucView® 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA)...

Fluorescent conjugates of recombinant cholera toxin subunit B. Can be used for tract-tracing in neurological research, targeting GM1 ganglioside binding and retrograde transport. Biotium's CF® dyes have superior brightness and photostability compared to other dyes. • Blue fluorescent CF®405M dye has...

Evaluate the performance of nucleic acid tests for determination of the presence of Influenza A H1 Virus nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix treated...

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SST4 is a member of the superfamily of receptors...

Prostaglandin D(2) (PGD(2)) is derived from arachidonic acid and binds with high affinity to the G-protein coupled receptors prostanoid DP(1) and DP(2). Interaction with DP(2) results in cell chemotaxis, eosinophil degranulation, eosinophil shape change, adhesion molecule upregulation and Th2...

Ciliary Neurotrophic Factor (CNTF) is a polypeptide hormone which acts within the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF is a potent survival factor for neurons and oligodendrocytes and may play a role in reducing...

AccuClear® Ultra High Sensitivity dsDNA Quantitation Solution utilizes a novel, next-generation DNA binding dye for highly sensitive and accurate quantitation of purified dsDNA samples across a broad range of DNA concentrations. The assay is linear between 0.03 ng and 250 ng of dsDNA per assay in...

Phalloidin conjugates are actin filament stains for fixed and permeabilized cells. Red fluorescent rhodamine phalloidin has excitation/emission at 540/565 nm.

MemBrite Fix 660/770 is a far-red fluorescent dye that covalently labels the surface of live cells. Unlike lipophilic membrane dyes, MemBrite is well-retained after fixation and permeabilization or methanol fixation.

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-3 activity by fluorescence in enzymatic reaction or mammalian cells. The fluorogenic substrate...

Zinquin is an UV-excitable, blue fluorescent zinc indicator. Zinquin ethyl ester is membrane-permeable and is hydrolyzed into Zinquin free acid once entering cells. Zinc is believed to be involved in the suppression of apoptosis and thought to play important roles in many neural activities.  ...