Life Science Reagents

Single donor specimens collected from donors prior to and continuing through disease progression.

KE00191 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The a-Synclein ELISA kit is to be used to detect and quantify protein levels of endogenous a-Synclein. The assay recognizes human a-Synclein. An antibody specific for a-Synclein has been pre-coated onto the...

CF® dye alkyne reacts with azide to form 1,2,3-triazole by copper(I) catalyzed 1,3-dipolar Huisgen cycloaddition. It can also be used as a monomer to copolymerize with other monomers to form fluorescent polymers. CF® dyes are Biotium's line of next-generation fluorescent dyes with advantages in...

Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Human Bone Morphogenetic Protein-2 (BMP-2) is synthesized as large precursor molecule (Met 1 -Arg 396 , with a signal peptide from Met 1 to Gly 23...

His-tag Antibody, pAb, Rabbit recognizes His tagged proteins in transfected or transformed cells. Short-sequence epitope tags are common in the study of protein expression in several different expression systems. In particular, the His tag on the expressed recombinant proteins allows for efficient...

Single donor specimens collected from donors prior to and continuing through disease progression.

CD4 is a 55 kDa glycoprotein that is a co-receptor for T cell receptor in T lymphocytes. CD4+ cells are essential for achieving effective immune response by associating with class II MHC molecules. 25%-65% human lymphocytes are CD4+. Human CD4 Isolation Kit is designed to isolate untouched CD4+ T...

Interleukin-8 is one of the first discovered chemokines, and belongs to the CXCL family, in which the first two conserved cysteines are separated by one residue. In vivo, IL-8 exists in two forms: 77 a.a. produced by endothelial cells, and the more active 72 a.a. produced by monocytes. The receptors...

Granulocyte Colony-Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The...

Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb....

Evaluate the performance of nucleic acid tests for determination of the presence of Clostridium difficile nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix...

The complement component 5a receptor 1 (C5a) is G_q/11 and G_i/o-coupled GPCRs. C5a is a significant pathogenic driver in a number of immuno-inflammatory diseases, making C5a inhibition an attractive therapeutic strategy. C5a receptor plays an important role in mediating acute...

DYKDDDDK (Flag) Tag Antibody Plate is a microtiter plate coated with THE™ Anti DYKDDDDK (Flag) Tag Antibody. The plate is designed for the rapid capturing of DYKDDDDK (Flag) tagged protein expressed in different systems, including, E. coli , yeast and mammalian extracts and cell culture...

ANTS (8-aminonaphthalene-1,3,6-trisulfonic acid, disodium salt) is a highly negatively charged dye with an amino group that can be coupled to an aldehyde or ketone group to form an unstable Schiff base. The Schiff base is usually chemically reduced by sodium borohydride (NaBH₄) or sodium...

Nerve Terminal Staining Kits contain Biotium's nerve terminal dyes and background reducing agents for washing away or quenching extracellular dye fluorescence. Kits are available with SynaptoGreen™ C4 (equivalent to FM®1-43), the fixable green nerve terminal dye AM1-43, or SynaptoRed™ C2 (equivalent...

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily and...

This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the...

Amine-reactive form of 5-carboxyfluorescein single isomer. &lamba;_Ex/&lamba; _Em(pH 9) = 495/519 nm Yellow orange solid soluble in DMF or DMSO Store at -20°C and protect from light C₂₅H₁₅NO₉ MW: 473.4 [92557-80-7]

Beta-actin is one of the six different actin isoforms that have been identified. The actin molecules found in cells of various species and tissues tend to be very similar in their immunological and physical properties. As a consequence, it has been difficult to produce potent antisera against this...

Fluorescein cadaverine can be coupled to activated carboxy groups or sulfonyl chlorides. • ? Ex/? Em(pH9) = 493/517 nm • Yellow solid soluble in DMSO, DMF, or pH>6.5 buffers • Store at 4°C and protect from light • C30H27F6N3O9S • MW: 719.61

Adenosine 3, 5-cyclic monophosphate (cyclic AMP; cAMP) is one of the most important intracellular secondary messengers for transduction events. cAMP is also involved in regulating neuronal, glandular, cardiovascular, immune, and other functions and actions. A number of hormones, such as ACTH, TSH,...

Membrane-impermeant calcium indicator that can be loaded into cells via microinjection or scrape loading.    K_d: 1 uM   &lamba;_Ex/&lamba; _Em (low or high [Ca 2 ])= 556nm/576nm   ε (556 nm) = 80,000 M -1 cm -1   Orange red solid...

Evaluate the performance of nucleic acid tests for determination of the presence of Influenza B Virus nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix treated...

PAR-4 agonist peptide stimulates thromboxane production by human platelets with the maximal response to this agonist being approximately half of that observed after maximal thrombin stimulation.