Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…

Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2,…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy and light chains of rat IgG and the light chains of rat IgM Source: Pepsin digest of Rabbit Anti-Rat IgG(H+L) (SB Cat. No. 6180) Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other rat immunoglobulins …

The monoclonal antibody 25-9-3 reacts specifically with the I-Ab haplotype of MHC Class II molecules. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells.

Specificity: Reacts with human ? light chains Source: Pepsin digest of Goat Anti-Human Kappa, Mouse ads (SB Cat. No. 2061) Cross Adsorption: Human ? light chains; mouse immunoglobulins and pooled sera; may react with ? light chains from other species Purification: Isotype: Goat…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy chain of mouse IgG3 Source: Pooled antisera from goats hyperimmunized with mouse IgG3 Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is…

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86…

Specificity: Reacts with the heavy chain of rat IgG Source: Pooled antisera from goats hyperimmunized with rat IgG Cross Adsorption: Rat IgM; may react with immunoglobulins from other species Purification: Affinity chromatography on pooled rat IgG covalently linked to agarose Isotype: …

CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage),…

CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of ?d+ T cells to more mature T cells…

Specificity: Reacts with the heavy and light chains of goat IgG Source: Pooled antisera from donkeys hyperimmunized with goat IgG Cross Adsorption: Mouse and rat serum proteins (SP); may react with immunoglobulins from other species and the light chains of other goat immunoglobulins …

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species Purification: …

CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy chains of mouse IgG1, IgG2a, IgG2b, IgG2c, and IgG3 Source: Pooled antisera from goats hyperimmunized with mouse IgG Cross Adsorption: Mouse IgM and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from goats hyperimmunized with human IgG Cross Adsorption: Mouse, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species …

CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgG2a…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

Specificity: Reacts with the heavy chain of mouse IgM Source: Pepsin digest of Goat Anti-Mouse IgM, Human ads (SB Cat. No. 1020) Cross Adsorption: Mouse IgG and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: Isotype: Goat…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy and light chains of goat IgG Source: Pooled antisera from rabbits hyperimmunized with goat IgG Cross Adsorption: Human serum proteins (SP); may react with immunoglobulins from other species and the light chains of other goat immunoglobulins Purification: …

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…