sCD40 Ligand, TRAP, rHusCD40L, human: CD40 ligand, CD40L (also known as CD154, TRAP or gp39), is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF family, CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, like NK cells,…

Description: Recombinant, full-length influenza hemagglutinin from virus strain A/JiangxiDonghu/346/2013 (H10N8). Recombinant hemagglutinin (rHA) is supplied as an affinity purified protein. rHA is produced in Sf9 insect cells using baculovirus for expression and is purified by FPLC. Size: 50…

MIP-2, CXCL2, murine (mouse): Macrophage Inflammatory Protein 2 (MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. Based on its protein and DNA sequences, MIP-2 is a member of the alpha (CXC)…

IL-11, Interleukin-11, murine (mouse): Interleukin 11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive murine plasmacytoma cell line T11. IL-11…

Oncostatin M (209 a.a.), human: Oncostatin M  (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and…

TFF2, Trefoil Factor 2, human: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. …

TFF1, Trefoil Factor 1, human: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and…

Description: Mature, recombinant, His-tagged Reston ebolavirus glycoprotein minus the transmembrane domain (rREBOV GPdTM) is supplied as purified protein. rREBOV GPdTM is produced in Sf9 insect cells using baculovirus for expression and is purified by column chromatography. Size: 100 µg…

IL-1 alpha, Interleukin-1 alpha, rat: Interleukin-1 alpha (IL-1α) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and…

IL-20, Interleukin-20, human: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a…

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic growth factor and immune modulator. GM-CSF also has profound effects on the functional activities of various circulating leukocytes.

CCL9, CCL10, murine (mouse): Macrophage Inflammatory Protein-1 gamma (MIP-1 gamma), also called MIP-2, belongs to the β (or CC) intercrine family of chemokines. It is further classified as a member of the NC6 or six cysteine-containing CC subfamily of chemokines. This subfamily…

NT-4, Neurotrophin-4, human: Neurotrophin-4 (NT-4), also known as NT-5, is a member of the NGF family of neuronal and epithelial growth factors. Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. Human NT-4 shares 48 - 52% aa…

TNF alpha Variant, Tumor Necrosis Factor-alpha Variant, human: The clinical use of the potent antitumor activity of TNF-αhas been limited by the proinflammatory side effects including fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing…

IL-31, Interleukin-31, human: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor).…

Protein G binds to the constant region of many species of immunoglobulin G. It can be used to detect, quantify and purify IgG antibodies and antibody/antigen complexes. Bio Basic Inc’s Recombinant Protein G contains only IgG binding domains. The albumin-binding domain as well as cell wall and…

The recombinant human protein APRIL has a gene ID of 8741. These proteins are lyophilized and are reconstituted with sterile PBS containing at least 0.1% carrier protein. The calculated M.W. of this protein is 16.4kDa. The proteins are expressed in a yeast system and endotoxin free.

Flt3-Ligand, CX3CL1, monkey (rhesus macaque): Flt-3 ligand (FL) is a recently identified hematopoietic cytokine whose activities are mediated by binding to the transmembrane glycoprotein Flt-3. Flt-3 was first discovered as a member of the class III subfamily of receptor tyrosine kinases (RTK)…

IL-2, Interleukin-2, porcine: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required…

IL-3, Interleukin-3, canine: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells…

IL-6, Interleukin-6, monkey (rhesus macaque): IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It…

Description: Staphylococcus aureus alpha hemolysin (Hla), also known as alpha toxin (α-toxin), is expressed in E. coli as a recombinant protein without TAG. The theoretical molecular weight of the protein is approximately 33 kDa. Size: 100 µg is supplied in phosphate buffered…

Description: : Purified, His-tagged Staphylococcus aureus PantonValentine Leukocidin (PVL) S subunit (LukS-PV). The theoretical molecular weight of the protein is 33,713 Daltons including the His-tag. Size: 100 ug of protein is supplied in PBS + 15% Glycerol at a concentration of 1 mg/mL.…

CDNF, human: Cerebral dopamine neurotrophic factor (CDNF), also known as ARMET-like protein 1, is encoded by the CDNF gene in humans and widely expressed in neuronal and non-neuronal tissues. The CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons…

SDF-1 beta, rHuSDF-1 beta, CXCL12, human: CXCL12 also known as SDF-1 is belonging to the CXC chemokine family. It is encoded by the CXCL12 gene. In recently study, Human CXCL12 is expressed as six isoforms that differ only in the C-terminal tail. And all SDF-1 isoforms undergo proteolytic…

Epigen, human: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially…

MIF, Migration Inhibitor Factor, human: Migration Inhibitory Factor (MIF) is a secreted protein without a cleavable signal sequence and is secreted via a specialized, non-classical pathway. It is secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.…

MIP-1 beta, CCL4, rat: Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a…

GM-CSF, Granulocyte Macrophage Colony Stimulating Factor, monkey (rhesus macaque): GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated…

EGF, Epidermal Growth Factor, rat: EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB,…

BAFF Receptor (rHuBAFF-R): BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds…

IL-1 alpha, Interleukin-1 alpha, murine (mouse): Murine Interleukin-1 alpha Interleukin-1 alpha (IL-1α) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic,…