JQ1 is a member of the triazolo-diazepine compound family, which functions as a pan-BET (bromodomain and extra-terminal motif) family inhibitor. JQ1 is known to suppress cell proliferation and therefore, can be used as a therapeutic drug for a number of cancers including multiple myeloma and acute…

Molecular Formula: C45H64FeNO3P2PdS Molecular Weight: 923.27 Linear Structural Formula: C45H64FeNO3P2PdS MDL Number: MFCD27978424

Synonyms: 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl]-3-pyridinecarboxamide Molecular Formula: C28H32N4O2S Molecular Weight: 488.64 Linear Structural Formula: C28H32N4O2S MDL Number: MFCD28334214 Purity: >=98% (HPLC) Storage: 2-8C …

Synonyms: Lithium 2-(phenylphosphonothioylamino)-3-phenylpropanoate Molecular Formula: C15H14NO3PS · 2Li Molecular Weight: 333.2 Linear Structural Formula: C15H14NO3PS · 2Li Purity: >=90% (NMR) Storage: 2-8C Biochem Physiol Actions: JK-2 is a phosphorothioate-based hydrogen…

Synonyms: N-[2-[(2-Methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide Molecular Formula: C16H16N4O2S2 Molecular Weight: 360.45 Linear Structural Formula: C16H16N4O2S2 MDL Number: MFCD02045222 Purity: >=98% (HPLC) Storage: 2-8C Biochem Physiol Actions: …

Product Source: expressed in Sf21 cells Biochem Physiol Actions: Target Sub-Family: CMGC Legal Information: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany Other Notes: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Synonym(s): C.I. 11050 Formula: C30H31ClN6 Formula weight: 511.07 CAS Number: 2869-83-2 Harmonized Tariff Code:  2933.59

Synonyms: 1,3,6,9-Tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-2H-purin-2-one; NSC 98003; NSC98003 Molecular Formula: C13H19N5O2S2 Molecular Weight: 341.45 Linear Structural Formula: C13H19N5O2S2 Purity: >=98% (HPLC) Storage: 2-8C Biochem Physiol…

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Synonyms: 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide; Piperidinium, 1-(1-cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethyl-, iodide (1:1), cis- Molecular Formula: C30H37Cl2IN2O2 Molecular…

Synonym(s): 4-(3-Amino-1H-indazol-4-yl)-N-(tert-butyl)benzenesulfonamide Formula: C17H20N4O2S Formula weight: 344.40 CAS Number: 1110502-30-1 Harmonized Tariff Code:  3504.00 Risk Phrases: 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: 24-37-60 Avoid…

Storage: room temp Application: JB-4 is a water-soluble, GMA based, plastic resin kit intended for use in the preparation of embedded samples for high resolution light microscopy. It is a technique now widely used for research and clinical diagnosis. JB-4 yields semi-thin sections (0.5mu-2mu)…

MDL No.: MFCD00166026 Storage: -20C UNSPSC Code: 12352204 Features and Benefits: . Reduces non-specific amplification. Increases PCR specificity and yield. Reduces set-up time concerns associated with manual or wax Hot Start methods. Activation time of less than 1…

Synonyms: N-[2-Methoxy-4-(4-morpholinyl)phenyl]-6-(1H-pyrazol-3-yl)-2-pyridinecarboxamide Molecular Formula: C20H21N5O3 Molecular Weight: 379.41 Linear Structural Formula: C20H21N5O3 Purity: >=98% (HPLC) Storage: 2-8C Biochem Physiol Actions: JH-I-25 is a potent and…

Product Source: recombinant, human JAK2, amino acids 808-end Application: Research CategoryInflammation & Immunology Biochem Physiol Actions: Target Sub-Family: TK Legal Information: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany Other Notes: For Specific…

Synonym(s): 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine Formula: C12H15N Formula weight: 173.26 Purity: 98% CAS Number: 479-59-4 Harmonized Tariff Code:  2933.99

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship…

Product Source: N-terminal GST-tagged, recombinant, human JAK1 amino acids 866-end, expressed by baculovirus in Sf21 insect cells. Activated in vitro by auto-phosphorylation. Application: Research CategorySignaling Biochem Physiol Actions: Target Sub-Family: TK Legal Information: …

Product Source: Expressed in Sf21 cells Biochem Physiol Actions: Target Sub-Family: CMGC Legal Information: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany Other Notes: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

MDL No.: MFCD00166026 Storage: -20C UNSPSC Code: 41106300 Features and Benefits: . JumpStart Taq DNA polymerase, an antibody inactivated hot start enzyme, is designed to minimize non-specific amplification while increasing target yield & specificity . JumpStart Taq DNA polymerase…

Synonyms: (alphaR)-alpha-Cyclopentyl-alpha-hydroxy-N-[1-(4-methyl-3-penten-1-yl)-4-piperidinyl]-Benzeneacetamide fumarate; J-104129 Molecular Formula: C24H36N2O2 · C4H4O4 Molecular Weight: 500.63 Linear Structural Formula: C24H36N2O2 · C4H4O4 MDL Number: MFCD09753272 Purity: …

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG Synonyms: 5-Hydroxy-1,4-naphthoquinone; Juglone…

Product Source: Expressed in Sf21 insect cells Biochem Physiol Actions: Target Sub-Family: CMGC Legal Information: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany Other Notes: For Specific Activity data, refer to the Certificate of Analysis for individual lots of…

Synonyms: 2-Methyl-5-phenyl-3-furancarboxylic acid; 2-Methyl-5-phenyl-3-furoic acid; 2-Methyl-5-phenylfuran-3-carboxylic acid; 5-Phenyl-2-methyl-3-furancarboxylic acid Molecular Formula: C12H10O3 Molecular Weight: 202.21 Linear Structural Formula: C12H10O3 Purity: >=98% (HPLC) …

Synonyms: 4-[[(3E,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-7-methyl-1-oxo-3-octen-1-yl]amino]-2,2,6,6-tetramethyl-1-piperidinyloxy; JP 4-039 Molecular Formula: C23H42N3O4 Molecular Weight: 424.6 Linear Structural Formula: C23H42N3O4 Purity: >=98% (HPLC) Storage: -20C …

Synonyms: 3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide Molecular Formula: C29H29N7O2 Molecular Weight: 507.59 Linear Structural Formula: C29H29N7O2 MDL Number: MFCD22124890 Purity: >=96% (HPLC) Storage:…

Synonyms: 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine CAS Number: 749886-87-1 Formula: C16H20N2 Formula Weight: 240.34 Linear Formula: C16H20N2 Purity: >=98% (HPLC) Storage: -20C UNSPSC Code: 12352200 Application: JSH-23 has been used as a nuclear factor κB (NF-κB) p65…

Synonyms: N-benzyl-2-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide Molecular Formula: C17H16ClNO3 Molecular Weight: 317.77 Linear Structural Formula: C17H16ClNO3 Purity: >=95% (HPLC) Storage: 2-8C Biochem Physiol Actions: JNS 1-40 is a potent and selective…

Synonyms: Jones reagent; Chromium trioxide solution in sulfuric acid; Sulfuric acid-chromium trioxide mixture CAS Number: 65272-70-0 MDL No.: MFCD22199316 Density: 1.298 g/mL at 25 C UNSPSC Code: 12352000 General description: Jones reagent is a solution of…

Synonyms: (CyYPhos)(Ph)PCy2; Tricyclohexyl((dicyclohexyl-phosphanyl)(phenyl)methylene)-phosphane Molecular Formula: C37H60P2 Molecular Weight: 566.82 Linear Structural Formula: C37H60P2 Melting Point: 205-214 C Application: joYPhos(TM) is an ylide-functionalized phosphine…

Synonyms: JackiePhos-Pd-G3; [(2-{Bis[3,5-bis(trifluoromethyl)phenyl]phosphine}-3,6-dimethoxy- 2',4',6'- triisopropyl-1,1'-biphenyl )-2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate Molecular Formula: C52H50F12NO5PPdS Molecular Weight: 1166.4 Linear Structural Formula: …

JQ1 is a member of the triazolo-diazepine compound family which functions as a pan-BET (bromodomain and extra-terminal motif) family inhibitor. Its core structure is composed of thienodiazepine. Synonyms: (R)-(-)-tert-Butyl…