Immunogen: peptide affinity-purified IgG Host: rabbit Species Reactivity: (+) human, bovine, and mouse sGC a1 subunit Application(s): WB Soluble guanylate cyclase is a heterodimeric enzyme, composed of α and β subunits, that synthesizes cGMP from GTP. The enzyme is activated…

Peptide sequences: human guanylate cyclase α subunit amino acids 418-436 (EQARAQDGLKKRLGKLKAT) To be used in conjunction with Cayman’s guanylate cyclase α subunit polyclonal antibody (Catalog No. 160895) to block protein-antibody complex formation during analysis for guanylate…

Antigen: human 11β-HSD2 amino acids 25-40 (RSDLRLGRPLLAALAL) Host: rabbit Cross Reactivity: (+) human, mouse, and rat 11β-HSD2 Application(s): WB 11β-HSD2 plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the…

Antigen: human COX-2 amino acids 578-596 Host: goat Cross-Reactivity: (+) human, ovine, mouse, rat COX-2; (−) COX-1 (all species) Application(s): WB, ICC, and IHC (formalin-fixed paraffin-embedded sections) Expression of COX-2, the inducible form of COX, is regulated by growth…

Antigen: purified enzyme from mouse macrophages (RAW 264.7 cells) Host: rabbit Cross Reactivity: (+) iNOS from most mammalian species and nNOS (~5%); (−) eNOS Application(s): ICC, IP, and WB NOS catalyzes the biosynthesis of nitric oxide from L-arginine. iNOS is a soluble enzyme…

Immunogen: synthetic peptide from C-terminal region of human optineurin Host: rabbit Species-Reactivity: (+) human optineurin Application(s): WB

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser301 of rat Raf-1 Host: rabbit Cross Reactivity: (+) rat Raf-1; expected to react with bovine, canine, chicken, human, mouse, non-human primate, and Xenopus Raf-1 Application(s): WB Studies have shown…

Antigen: rat soluble guanylate cyclase β1 subunit (soluble) amino acids 188-207 Host: rabbit Cross Reactivity: (+) human, bovine, and rat soluble guanylate cyclase β1 subunit; (−) α1 subunit Application(s): IHC and WB Soluble guanylate cyclase is a heterodimeric…

Antigen: native bovine ubiquitin conjugated to KLH Host: rabbit Cross Reactivity: (+) human, monkey, mouse, rat, hamster, rabbit, guinea pig, bovine, porcine, canine, pvine, chicken, Xenopus, yeast, Drosophila, and Rainbow Trout ubiquitin Application(s): WB, IP, and ChIP Ubiquitin…

Product is the lyophilized powder of horseradish peroxidase (HRP)-conjugated goat IgG fraction to human albumin and buffer salts. Antibody and highly purified HRP (Rz>3.0) are conjugated under defined conditions to obtain optimally labeled product. Conjugated protein is purified by salt…

Immunogen: synthetic peptide from the N-terminal region of human protein Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and bovine β-catenin Application(s): IHC and WB β-Catenin is a multifunctional protein known to be part of the Wnt pathway, playing essential…

Peroxidase-Conjugated Goat IgG Fraction To Human Complement C3 is the lyophilized powder of horseradish peroxidase (HRP)-conjugated goat IgG fraction to human complement C3 and buffer salts. Background Information Complement component C3 plays a central role in the activation of complement…

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human β-catenin Host: rabbit Cross-reactivity: (+) human β-catenin Application: WB β-Catenin is a central component of the cadherin cell adhesion complex and plays an…

Product is the lyophilized powder of goat antiserum to mouse complement C3 and buffer salts. Background Information The complement system provides innate defense against microbial infection and is a "complement" to antibody mediated immunity. The complement system consists of…

Antigen: mouse/rat COX-2 amino acids 570-598 Host: rabbit Cross-Reactivity: (+) human, guinea pig, monkey, mouse, ovine, rabbit, and rat COX-2; (−) COX-1 (all species) Application(s): ICC, IHC, and WB

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3β Host: rabbit Cross Reactivity: (+) rat GSK3β; expected to react with human, bovine, canine, chicken, mouse, non-human primate, Xenopus, and zebrafish GSK3β Application(s): WB …

Peptide Sequence: human 11β-HSD1 amino acids 78-92 (CLELGAASAHYLAGT) To be used in conjunction with Cayman’s 11β-HSD1 polyclonal antibody (Catalog No. 10004303) to block protein-antibody complex formation during immunochemical analysis of 11β-HSD1.

11-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the pathophysiology of hypertension by converting active cortisol to inactive cortisone. Mutation in the gene encoding 11β-HSD2 results…

Antigen: Peptide from the C-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human, mouse, and non-human primate tissue DBH Application: WB

Antigen: human 11β-HSD1 amino acids 78-92 (CLELGAASAHYIAGT) Host: rabbit Cross-reactivity: (+) human, mouse, and rat 11β-HSD1 Applications: IHC (formalin-fixed paraffin-embedded tissue) and WB 11β-HSD1 catalyzes the conversion of inactive cortisone to active cortisol in…

Antigen: Peptide from the N-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human and non-human primate tissue DBH Application: WB

This antibody is designed for specific and qualitative detection of Toxoplasma gondii in infected tissues. Formalin-fixed paraffin-embedded and frozen tissue sections can be used. Characterization of this antibody by immunohistochemistry has shown specific staining for Toxoplasma organisms in…

Immunogen: peptide from the C-terminal region of human BLT2 Host: rabbit Species Reactivity: (+) human and mouse BLT2 receptor Application(s): WB

Antigen: recombinant human Nod2 residues 28-301 Host: rabbit Application(s): WB and IP; may not detect basal levels of Nod2 in monocytes

Product is the lyophilized powder of fluorescein-5-isothiocyanate (FITC "Isomer I")-conjugated goat IgG fraction to guinea pig complement C3 and buffer salts. Background Information The complement system provides innate defense against microbial infection and is a…

Immunogen: synthetic peptide from the N-terminal region of human H-PGDS Host: rabbit Species Reactivity: (+) human, baboon, mouse, and rat H-PGDS Application(s): WB

Antigen: human DcR2 precursor amino acids 249-263 Host: rabbit Cross Reactivity: (+) human DcR2 Application(s): WB DcR2 has an extracellular TRAIL-binding domain but lacks an intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed…

Immunogen: peptide from an internal region of ovine COX-1 Host: rabbit Cross reactivity: (-) ovine, human, and mouse COX-2 Species reactivity: (+) ovine seminal vesicle, human, bovine endothelial, and porcine COX-1 Applications: WB, ICC, IHC

Product is the lyophilized powder of goat IgG fraction to chicken egg albumin and buffer salts. Applications Goat IgG Fraction to Chicken Egg Albumin is suitable for use as a precipitating antibody. It gives sharp precipitin lines in immunoelectrophoresis and immunodiffusion techniques. It is…

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr34 of rat DARPP-32 Host: rabbit Cross Reactivity: (+) rat DARPP-32 Application(s): WB DARPP-32 is a dopamine and cAMP-regulated phosphoprotein that plays a critical role in the regulation of dopaminergic…

Antigen: synthetic peptide corresponding to human IRAK-1 amino acids 700-712 Host: rabbit Cross Reactivity: (+) human and mouse IRAK-1; (−) IRAK-2 Application(s): IP and WB IRAK-1 is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a…

Peptide Sequence: soluble rat guanylate cyclase β1 subunit, amino acids 188-207 (EDFYEDLDRFEENGTQDSR; last D=E in human and bovine) To be used in conjunction with Cayman’s guanylate cyclase β1 subunit (soluble) polyclonal antibody (Catalog No. 160897) to block protein-antibody…