| Protective Clothing (Pictograms) |
 |
 |
 |
 |
| Section 1. Product and Company Identification |
| Product Name | Tris-Hydrochloride | Product Code | 9350 |
|
|
|
|
| For More Information Call | In Case of Emergency Call |
| 856-423-6300 Technical Service
Monday-Friday: 8:00 AM - 5:00 PM |
800-424-9300 CHEMTREC (USA)
613-996-6666 CANUTEC (Canada) 24 Hours/Day: 7 Days/Week |
| Synonym | 1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-, HYDROCHLORIDE |
| Material Uses | Analytical reagent.
|
| Chemical Family | Organic salt |
| Section 2. Composition and Information on Ingredients |
| Component | CAS # | % by Weight |
| Tris (Hydroxymethyl)ammiomethane hydrochloride | 1185-53-1 | 100 |
| Section 3. Hazards Identification |
| Physical State and Appearance | Solid,Crystalline Powder |
| Emergency Overview | CAUTION !
MAY BE HARMFUL IF SWALLOWED. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE ALLERGIC SKIN REACTION. |
| Routes of Entry | Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion. |
| Potential Acute Health Effects |
| Eyes | Hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching. |
| Skin | Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. May be hazardous in case of skin contact (sensitizer). |
| Inhalation | Hazardous in case of inhalation (lung irritant). |
| Ingestion | May be hazardous in case of ingestion. |
| Potential Chronic Health Effects |
| Carcinogenic Effects | This material is not known to cause cancer in animals or humans. |
| Additional information See Toxicological Information (section 11) |
| Medical Conditions Aggravated by Overexposure: | Repeated or prolonged exposure is not known to aggravate medical condition. |
| Section 4. First Aid Measures |
| Eye Contact | Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention immediately. |
| Skin Contact | In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately. |
| Inhalation | If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. |
| Ingestion | Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. |
| Section 5. Fire Fighting Measures |
| Flammability of the Product | Non-flammable. |
| Auto-ignition Temperature | Not applicable. |
| Flash Points | Not applicable. |
| Flammable Limits | Not applicable. |
| Products of Combustion | Not applicable. |
| Fire Hazards in Presence of Various Substances | Not applicable. |
| Explosion Hazards in Presence of Various Substances | Risks of explosion of the product in presence of static discharge: No.
Risks of explosion of the product in presence of mechanical impact: No. |
| Fire Fighting Media
and Instructions |
Not applicable. |
| Protective Clothing (Fire) | Not applicable. |
| Special Remarks on Fire Hazards | Not available. |
| Special Remarks on Explosion Hazards | Not available. |
| Section 6. Accidental Release Measures |
| Small Spill and Leak | Use appropriate tools to put the spilled solid in a convenient waste disposal container. |
| Large Spill and Leak | Use a shovel to put the material into a convenient waste disposal container. |
| Spill Kit Information | No specific spill kit required for this product. |
| Section 7. Handling and Storage |
| Handling | Avoid contact with eyes. Do not ingest. Avoid breathing dust. Avoid prolonged or repeated contact with skin. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. |
| Storage | Keep container tightly closed. Keep container in a cool, well-ventilated area. |
| Section 8. Exposure Controls/Personal Protection |
| Engineering Controls | Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. |
| Personal Protection |
| Eyes | Splash goggles. |
| Body | Lab coat. |
| Respiratory | Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. |
| Hands | Gloves. |
| Feet | Not applicable. |
|
|
| Personal Protection in Case of a Large Spill | Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. |
| Product Name | Exposure Limits |
| Tris (Hydroxymethyl)ammiomethane hydrochloride | Not available. |
| Section 9. Physical and Chemical Properties |
| Odor | Odorless. |
| Color | White. |
| Physical State and Appearance | Solid,Crystalline Powder |
| Molecular Weight | Not available. |
| Molecular Formula | C4H11NO3.ClH |
| pH | Not available. |
| Boiling/Condensation Point | Not available. |
| Melting/Freezing Point | 151°C (303.8°F) |
| Specific Gravity | Not available. |
| Vapor Pressure | Not available. |
| Vapor Density | Not available. |
| Odor Threshold | Not available. |
| Evaporation Rate | Not available. |
| LogKow | Not available. |
| Solubility | Soluble in water. |
| Section 10. Stability and Reactivity |
| Stability and Reactivity | The product is stable. |
| Conditions of Instability | Hygroscopic; keep container tightly closed. |
| Incompatibility with Various Substances | Highly reactive with oxidizing agents. |
| Rem/Incompatibility | Avoid excessive heat. Incompatable with Strong Bases |
| Hazardous Decomposition Products | These products are halogenated compounds, hydrogen chloride. NOx COx |
| Hazardous Polymerization | Will not occur. |
| Section 11. Toxicological Information |
| RTECS Number: |
| Tris-Hydrochloride | Not available. |
| Toxicity | LD50: Not available.
LC50: Not available. |
| Chronic Effects on Humans | Not available. |
| Acute Effects on Humans | Hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching. Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. May be hazardous in case of skin contact (sensitizer). Hazardous in case of inhalation (lung irritant). May be hazardous in case of ingestion. |
| Synergetic Products (Toxicologically) | Not available. |
| Irritancy | Draize Test: Not available. |
| Sensitization | Hazardous in case of skin contact (sensitizer). |
| Carcinogenic Effects | This material is not known to cause cancer in animals or humans. |
| Toxicity to Reproductive System | Not available. |
| Teratogenic Effects | Not available. |
| Mutagenic Effects | Not available. |
| Section 12. Ecological Information |
| Ecotoxicity | Not available. |
| BOD5 and COD | Not available. |
| Toxicity of the Products of Biodegradation | The products of degradation are as toxic as the product itself. |
| Section 13. Disposal Considerations |
| EPA Waste Number | Not available. |
| Treatment | Material does not have an EPA Waste number and is not a listed waste, however consultation with a permitted waste disposal site (TSD) should be accomplished.
ALWAYS CONTACT A PERMITTED WASTE DISPOSER (TSD) TO ASSURE COMPLIANCE WITH ALL CURRENT LOCAL, STATE AND FEDERAL REGULATIONS. |
| Section 14. Transport Information |
| DOT Classification | Proper Shipping Name: CHEMICALS, N.O.S.
RQ: Not applicable. |
| TDG Classification | Not available. |
| IMO/IMDG Classification | Not available. |
| ICAO/IATA Classification | Proper Shipping Name: CHEMICALS, N.O.S.
RQ: Not applicable. |
| Section 15. Regulatory Information |
| U.S. Federal Regulations | TSCA 8(b) inventory: Tris (Hydroxymethyl)ammiomethane hydrochloride |
| SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. |
| SARA 313 toxic chemical notification and release reporting: No products were found. |
| Clean Water Act (CWA) 307: No products were found. |
| Clean Water Act (CWA) 311: No products were found. |
| Clean air act (CAA) 112 accidental release prevention: No products were found. |
| Clean air act (CAA) 112 regulated flammable substances: No products were found. |
| Clean air act (CAA) 112 regulated toxic substances: No products were found. |
| WHMIS (Canada) | Class D-2B: Material causing other toxic effects (TOXIC).
|
| CEPA DSL: Tris (Hydroxymethyl)ammiomethane hydrochloride |
| This product has been classiifed in accordance with the hazard criteria of the Controlled Product Regulations and the MSDS contains all required information. |
| International Regulations |
| EINECS | Tris (Hydroxymethyl)ammiomethane hydrochloride 214-684-5 |
| DSCL (EEC) | R37/38- Irritating to respiratory system and skin.
R41- Risk of serious damage to eyes. R43- May cause sensitization by skin contact. |
| International Lists | Australia (NICNAS): Tris (Hydroxymethyl)ammiomethane hydrochloride
Japan (MITI): Tris (Hydroxymethyl)ammiomethane hydrochloride Korea (TCCL): Tris (Hydroxymethyl)ammiomethane hydrochloride Philippines (RA6969): Tris (Hydroxymethyl)ammiomethane hydrochloride |
| China: No products were found. |
| State Regulations | New Jersey: Tris (Hydroxymethyl)ammiomethane hydrochloride |
| California prop. 65: No products were found. |
| Section 16. Other Information |
|
|
|
|
| Changed Since Last Revision | + |
| Notice to Reader |
| The statements contained herein are based upon technical data that EMD Chemicals Inc. believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. EMD CHEMICALS INC. MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. |