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| Section 1. Product and Company Identification |
| Product Name | 10XTBE Buffer, Liquid Concentrate, OmniPur ® , For Molecular Biology | Product Code | 8820 |
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| For More Information Call | In Case of Emergency Call |
| 856-423-6300 Technical Service
Monday-Friday: 8:00 AM - 5:00 PM |
800-424-9300 CHEMTREC (USA)
613-996-6666 CANUTEC (Canada) 24 Hours/Day: 7 Days/Week |
| Synonym | None. |
| Material Uses | Analytical reagent.
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| Chemical Family | Solution. |
| Section 2. Composition and Information on Ingredients |
| Component | CAS # | % by Weight |
| Water | 7732-18-5 | 70-90 |
| Boric Acid | 10043-35-3 | 0-10 |
| EDTA di-Sodium Dihydrate | 6381-92-6 | 0-10 |
| Tris (hydroxymethyl) aminomethane | 77-86-1 | 10-20 |
| Section 3. Hazards Identification |
| Physical State and Appearance | Liquid. |
| Emergency Overview | CAUTION!
CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY BE HARMFUL IF SWALLOWED. |
| Routes of Entry | Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion. |
| Potential Acute Health Effects |
| Eyes | Hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching. |
| Skin | Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. |
| Inhalation | Hazardous in case of inhalation (lung irritant). |
| Ingestion | May be hazardous in case of ingestion. |
| Potential Chronic Health Effects |
| Carcinogenic Effects | This material is not known to cause cancer in animals or humans. |
| Additional information See Toxicological Information (section 11) |
| Medical Conditions Aggravated by Overexposure: | Repeated or prolonged exposure is not known to aggravate medical condition. |
| Section 4. First Aid Measures |
| Eye Contact | Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention immediately. |
| Skin Contact | In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately. |
| Inhalation | If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. |
| Ingestion | Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. |
| Section 5. Fire Fighting Measures |
| Flammability of the Product | Non-flammable. |
| Auto-ignition Temperature | Not applicable. |
| Flash Points | Not applicable. |
| Flammable Limits | Not applicable. |
| Products of Combustion | Not available. |
| Fire Hazards in Presence of Various Substances | Not applicable. |
| Explosion Hazards in Presence of Various Substances | Risks of explosion of the product in presence of static discharge: No.
Risks of explosion of the product in presence of mechanical impact: No. |
| Fire Fighting Media
and Instructions |
Not applicable. |
| Protective Clothing (Fire) | Not applicable. |
| Special Remarks on Fire Hazards | Not available. |
| Special Remarks on Explosion Hazards | May emit toxic fumes under fire conditions.
Thermal decomposition may release toxic and/or hazardous gases. (EDTA di-Sodium Dihydrate) |
| Section 6. Accidental Release Measures |
| Small Spill and Leak | Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. |
| Large Spill and Leak | Absorb with an inert material and put the spilled material in an appropriate waste disposal. |
| Spill Kit Information | No specific spill kit required for this product. |
| Section 7. Handling and Storage |
| Handling | Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing vapors or spray mists. Keep container closed. |
| Storage | Keep container in a cool, well-ventilated area. |
| Section 8. Exposure Controls/Personal Protection |
| Engineering Controls | Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective occupational exposure limits. |
| Personal Protection |
| Eyes | Splash goggles. |
| Body | Lab coat. |
| Respiratory | Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. |
| Hands | Gloves. |
| Feet | Not applicable. |
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| Personal Protection in Case of a Large Spill | Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. |
| Product Name | Exposure Limits |
| Water | Not available. |
| Boric Acid | Not available. |
| EDTA di-Sodium Dihydrate | Not available. |
| Tris (hydroxymethyl) aminomethane | Not available. |
| Section 9. Physical and Chemical Properties |
| Odor | Not available. |
| Color | Colorless. |
| Physical State and Appearance | Liquid. |
| Molecular Weight | Not applicable. |
| Molecular Formula | Not applicable. |
| pH | Not available. |
| Boiling/Condensation Point | The lowest known value is 99.9°C (211.8°F) (WATER). |
| Melting/Freezing Point | May start to solidify at -0.1°C (31.8°F) based on data for: WATER. |
| Specific Gravity | The only known value is 1.51 (Water = 1) (BORIC ACID). |
| Vapor Pressure | Not available. |
| Vapor Density | Not available. |
| Odor Threshold | Not available. |
| Evaporation Rate | 0.36 (WATER) compared to (n-BUTYL ACETATE=1) |
| LogKow | Not available. |
| Solubility | Soluble in water. |
| Section 10. Stability and Reactivity |
| Stability and Reactivity | The product is stable. |
| Conditions of Instability | Not available. |
| Incompatibility with Various Substances | Slightly reactive to reactive with oxidizing agents, metals, alkalis. |
| Rem/Incompatibility | Avoid generating dust or vapors. Extreme heat (EDTA di-Sodium Dihydrate) |
| Hazardous Decomposition Products | Not available. |
| Hazardous Polymerization | Will not occur. |
| Section 11. Toxicological Information |
| RTECS Number: |
| Water | ZC0110000 |
| Boric Acid | ED4550000 |
| EDTA di-Sodium Dihydrate | Not available. |
| Tris (hydroxymethyl) aminomethane | TY2900000 |
| Toxicity | Acute oral toxicity (LD50): 14447 mg/kg (Rat) (Calculated value for the mixture). |
| Chronic Effects on Humans | Not available. |
| Acute Effects on Humans | Hazardous in case of eye contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching. Hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Hazardous in case of inhalation (lung irritant). May be hazardous in case of ingestion. |
| Synergetic Products (Toxicologically) | Not available. |
| Irritancy | Draize Test: Not available. |
| Sensitization | Not available. |
| Carcinogenic Effects | This material is not known to cause cancer in animals or humans. |
| Toxicity to Reproductive System | Not available. |
| Teratogenic Effects | Not available. |
| Mutagenic Effects | Not available. |
| Section 12. Ecological Information |
| Ecotoxicity | Not available. |
| BOD5 and COD | Not available. |
| Toxicity of the Products of Biodegradation | The products of degradation are less toxic than the product itself. |
| Section 13. Disposal Considerations |
| EPA Waste Number | Not available. |
| Treatment | Material does not have an EPA Waste Number and is not a listed waste, however consultation with a permitted waste disposal site (TSD) should be accomplished. Always contact a permitted waste disposal (TSD) to assure compliance with all current local, state, and Federal Regulations.. |
| Section 14. Transport Information |
| DOT Classification | Proper Shipping Name: CHEMICALS, N.O.S.
RQ: Not applicable. |
| TDG Classification | Not available. |
| IMO/IMDG Classification | Proper Shipping Name: CHEMICALS, N.O.S.
RQ: Not applicable. |
| ICAO/IATA Classification | Proper Shipping Name: CHEMICALS, N.O.S.
RQ: Not applicable. |
| + | Section 15. Regulatory Information |
| U.S. Federal Regulations | TSCA 8(b) inventory: Water; Boric Acid; EDTA di-Sodium Dihydrate; Tris (hydroxymethyl) aminomethane |
| SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: Boric Acid; EDTA di-Sodium Dihydrate; Tris (hydroxymethyl) aminomethane SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Boric Acid: Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard; EDTA di-Sodium Dihydrate: Immediate (Acute) Health Hazard; Tris (hydroxymethyl) aminomethane: Immediate (Acute) Health Hazard |
| SARA 313 toxic chemical notification and release reporting: No products were found. |
| Clean Water Act (CWA) 307: No products were found. |
| Clean Water Act (CWA) 311: No products were found. |
| Clean air act (CAA) 112 accidental release prevention: No products were found. |
| Clean air act (CAA) 112 regulated flammable substances: No products were found. |
| Clean air act (CAA) 112 regulated toxic substances: No products were found. |
| WHMIS (Canada) | Class D-2B: Material causing other toxic effects (TOXIC).
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| CEPA DSL: Water; Boric Acid; Tris (hydroxymethyl) aminomethane |
| This product has been classifed in accordance with the hazard criteria of the Controlled Product Regulations and the MSDS contains all required information. |
| International Regulations |
| EINECS | Water 231-791-2
Boric Acid 233-139-2 EDTA di-Sodium Dihydrate 205-358-3 Tris (hydroxymethyl) aminomethane 201-064-4 |
| DSCL (EEC) | R37/38- Irritating to respiratory system and skin.
R41- Risk of serious damage to eyes. |
| International Lists | Australia (NICNAS): Water; Boric Acid; Tris (hydroxymethyl) aminomethane
Japan (MITI): Water; Boric Acid; Tris (hydroxymethyl) aminomethane Korea (TCCL): Water; Boric Acid; Tris (hydroxymethyl) aminomethane Philippines (RA6969): Water; Boric Acid; Tris (hydroxymethyl) aminomethane |
| China: No products were found. |
| State Regulations | New Jersey: EDTA di-Sodium Dihydrate; Tris (hydroxymethyl) aminomethane |
| California prop. 65: No products were found. |
| Section 16. Other Information |
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| Changed Since Last Revision | + |
| Notice to Reader |
| The statements contained herein are based upon technical data that EMD Chemicals Inc. believes to be reliable, are offered for information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly trained person having the necessary technical skills. Users should consider these data only as a supplement to other information gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the protection of the environment. EMD CHEMICALS INC. MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE, WITH RESPECT TO THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. |
